Cardiac fibroblasts mediate IL-17A–driven inflammatory dilated cardiomyopathy

Inflammatory dilated cardiomyopathy (DCMi) is a major cause of heart failure in individuals below the age of 40. We recently reported that IL-17A is required for the development of DCMi. We show a novel pathway connecting IL-17A, cardiac fibroblasts (CFs), GM-CSF, and heart-infiltrating myeloid cell...

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Main Authors: Wu, Lei, Ong, SuFey, Talor, Monica V., Barin, Jobert G., Baldeviano, G. Christian, Kass, David A., Bedja, Djahida, Zhang, Hao, Sheikh, Asfandyar, Margolick, Joseph B., Iwakura, Yoichiro, Rose, Noel R., Čiháková, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076595/
https://ncbi.nlm.nih.gov/pubmed/24935258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132126
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