Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy

Loss of cell cycle controls is a hallmark of cancer and has a well-established role in aggressive B cell malignancies. However, the role of such lesions in indolent follicular lymphoma (FL) is unclear and individual lesions have been observed with low frequency. By analyzing genomic data from two la...

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Autors principals: Oricchio, Elisa, Ciriello, Giovanni, Jiang, Man, Boice, Michael H., Schatz, Jonathan H., Heguy, Adriana, Viale, Agnes, de Stanchina, Elisa, Teruya-Feldstein, Julie, Bouska, Alyssa, McKeithan, Tim, Sander, Chris, Tam, Wayne, Seshan, Venkatraman E., Chan, Wing-Chung, Chaganti, R.S.K., Wendel, Hans-Guido
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076578/
https://ncbi.nlm.nih.gov/pubmed/24913233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132120
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