The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma

Insights into cancer genetics can lead to therapeutic opportunities. By cross-referencing chromosomal changes with an unbiased genetic screen we identify the ephrin receptor A7 (EPHA7) as a tumor suppressor in follicular lymphoma (FL). EPHA7 is a target of 6q deletions and inactivated in 72 % of FLs...

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Autors principals: Oricchio, Elisa, Nanjangud, Gourd, Wolfe, Andrew L., Schatz, Jonathan H., Mavrakis, Konstantinos J., Jiang, Man, Liu, Xiaoping, Bruno, Joanne, Heguy, Adriana, Olshen, Adam B., Socci, Nicholas D., Teruya-Feldstein, J., Weis-Garcia, Frances, Tam, Wayne, Shaknovich, Rita, Melnick, Ari, Himanen, Juha P., Chaganti, R.S.K., Wendel, Hans-Guido
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208379/
https://ncbi.nlm.nih.gov/pubmed/22036564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.035
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