MFG-E8 Regulates Angiogenesis in Cutaneous Wound Healing

Our research group recently demonstrated that pericytes are major sources of the secreted glycoprotein and integrin ligand lactadherin (MFG-E8) in B16 melanoma tumors, and that MFG-E8 promotes angiogenesis via enhanced PDGF–PDGFRβ signaling mediated by integrin–growth factor receptor crosstalk. Howe...

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Bibliografiske detaljer
Main Authors: Uchiyama, Akihiko, Yamada, Kazuya, Ogino, Sachiko, Yokoyama, Yoko, Takeuchi, Yuko, Udey, Mark C., Ishikawa, Osamu, Motegi, Sei-ichiro
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2014
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076467/
https://ncbi.nlm.nih.gov/pubmed/24838098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.03.017
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