Pericyte-Derived MFG-E8 Regulates Pathologic Angiogenesis

OBJECTIVE: MFG-E8 (lactadherin, SED1) is a secreted glycoprotein that has been previously implicated in enhancement of VEGF-dependent angiogenesis. Major sources of MFG-E8 in vivo, and precise mechanisms of MFG-E8 action remain undetermined. The objective of this study was to identify important sour...

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Main Authors: Motegi, Sei-ichiro, Leitner, Wolfgang W., Lu, Michael, Tada, Yayoi, Sárdy, Miklós, Wu, Chuanjin, Chavakis, Triantafyllos, Udey, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184509/
https://ncbi.nlm.nih.gov/pubmed/21737783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.232587
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