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Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst

In embryonic stem (ES) cells and in early mouse embryos, the transcription factor Oct4 is an essential regulator of pluripotency. Oct4 transcriptional targets have been described in ES cell lines; however, the molecular mechanisms by which Oct4 regulates establishment of pluripotency in the epiblast...

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Bibliografische gegevens
Hoofdauteurs: Frum, Tristan, Halbisen, Michael A., Wang, Chaoyang, Amiri, Hossein, Robson, Paul, Ralston, Amy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076445/
https://ncbi.nlm.nih.gov/pubmed/23747191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.05.004
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