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Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer

Based on the growing evidence that G-protein coupled receptors (GPCRs) form homo- and hetero-oligomers, models of GPCR signaling are now considering macromolecular assemblies rather than monomers, with the homo-dimer regarded as the minimal oligomeric arrangement required for functional coupling to...

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Detalhes bibliográficos
Main Authors: Filizola, Marta, Wang, Simon X., Weinstein, Harel
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076291/
https://ncbi.nlm.nih.gov/pubmed/17089205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-006-9053-3
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