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Phenotypic Characterization of miR-92a(−/−) Mice Reveals an Important Function of miR-92a in Skeletal Development
MicroRNAs (miRNAs, miRs) emerged as key regulators of gene expression. Germline hemizygous deletion of the gene that encodes the miR-17∼92 miRNA cluster was associated with microcephaly, short stature and digital abnormalities in humans. Mice deficient for the miR-17∼92 cluster phenocopy several fea...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4076267/ https://ncbi.nlm.nih.gov/pubmed/24979655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101153 |
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