miR-25 and miR-92a regulate insulin I biosynthesis in rats

The 3′ UTR of insulin has been identified as a critical region that confers mRNA stability, which is crucial for promoting transcription in response to glucose challenge. miRNAs are endogenously encoded non-coding RNAs that function as regulators of gene expression. This regulatory function is gener...

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Autores principales: Setyowati Karolina, Dwi, Sepramaniam, Sugunavathi, Tan, Hui Zhing, Armugam, Arunmozhiarasi, Jeyaseelan, Kandiah
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817158/
https://ncbi.nlm.nih.gov/pubmed/24084692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.25557
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