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miR-25 and miR-92a regulate insulin I biosynthesis in rats
The 3′ UTR of insulin has been identified as a critical region that confers mRNA stability, which is crucial for promoting transcription in response to glucose challenge. miRNAs are endogenously encoded non-coding RNAs that function as regulators of gene expression. This regulatory function is gener...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817158/ https://ncbi.nlm.nih.gov/pubmed/24084692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.25557 |
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