The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer

The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistance. This study aims to provide further evidence th...

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Main Authors: d'Adhemar, Charles J., Spillane, Cathy D., Gallagher, Michael F., Bates, Mark, Costello, Katie M., Barry-O'Crowley, Jacqui, Haley, Kathryn, Kernan, Niamh, Murphy, Ciara, Smyth, Paul C., O'Byrne, Ken, Pennington, Stephen, Cooke, Aoife A., Ffrench, Brendan, Martin, Cara M., O'Donnell, Dearbhaile, Hennessy, Bryan, Stordal, Britta, Finn, Stephen, McCann, Amanda, Gleeson, Noreen, D'Arcy, Tom, Flood, Brian, O'Neill, Luke A. J., Sheils, Orla, O'Toole, Sharon, O'Leary, John J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076208/
https://ncbi.nlm.nih.gov/pubmed/24977712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100816
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