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A Genotype-First Approach to Defining the Subtypes of a Complex Disease

Medical genetics typically entails the detailed characterization of a patient’s phenotypes followed by genotyping to discover the responsible gene or mutation. Here, we propose that the systematic discovery of genetic variants associated with complex diseases such as autism are progressing to a poin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stessman, Holly A., Bernier, Raphael, Eichler, Evan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076166/
https://ncbi.nlm.nih.gov/pubmed/24581488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.02.002
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