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A Genotype-First Approach to Defining the Subtypes of a Complex Disease

Medical genetics typically entails the detailed characterization of a patient’s phenotypes followed by genotyping to discover the responsible gene or mutation. Here, we propose that the systematic discovery of genetic variants associated with complex diseases such as autism are progressing to a poin...

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Bibliografiske detaljer
Main Authors: Stessman, Holly A., Bernier, Raphael, Eichler, Evan E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076166/
https://ncbi.nlm.nih.gov/pubmed/24581488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.02.002
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