Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient mice have shown that this lipid chaperone has a significant role in several aspects of metabolic syndrome, including type 2 diab...

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Detalhes bibliográficos
Main Authors: Furuhashi, Masato, Tuncman, Gürol, Görgün, Cem Z., Makowski, Liza, Atsumi, Genichi, Vaillancourt, Eric, Kono, Keita, Babaev, Vladimir R., Fazio, Sergio, Linton, MacRae F., Sulsky, Richard, Robl, Jeffrey A., Parker, Rex A., Hotamisligil, Gökhan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076119/
https://ncbi.nlm.nih.gov/pubmed/17554340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05844
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