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Rosiglitazone-loaded Nanospheres for Modulating Macrophage-Specific Inflammation in obesity

PPARγ nuclear receptor agonists have been shown to attenuate macrophage inflammatory responses implicated in the metabolic complications of obesity and in atherosclerosis. However, PPARγ agonists currently in clinical use, including rosiglitazone (RSG), are often associated with severe side effects...

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Detalhes bibliográficos
Main Authors: Di Mascolo, Daniele, Lyon, Christopher, Aryal, Santosh, Ramirez, Maricela R., Wang, Jun, Candeloro, Patrizio, Guindani, Michele, Hsueh, Willa A., Decuzzi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076002/
https://ncbi.nlm.nih.gov/pubmed/23791978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.06.012
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