Yhhu3813 is a novel selective inhibitor of c-Met Kinase that inhibits c-Met-dependent neoplastic phenotypes of human cancer cells

AIM: c-Met kinase deregulation is strongly associated with the formation, progression and dissemination of human cancers. In this study we identified Yhhu3813 as a small-molecule inhibitor of c-Met kinase and characterized its antitumor properties both in vitro and in vivo. METHODS: The activities o...

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Main Authors: He, Chang-xi, Ai, Jing, Xing, Wei-qiang, Chen, Yi, Zhang, Hao-tian, Huang, Min, Hu, You-hong, Ding, Jian, Geng, Mei-yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075751/
https://ncbi.nlm.nih.gov/pubmed/24241352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.125
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