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A single-molecule long-read survey of the human transcriptome

Global RNA studies have become central to understanding biological processes, but methods such as microarrays and short-read sequencing are unable to describe an entire RNA molecule from 5′ to 3′ end. Here we use single-molecule long-read sequencing technology from Pacific Biosciences to sequence th...

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Hlavní autoři: Sharon, Donald, Tilgner, Hagen, Grubert, Fabian, Snyder, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075632/
https://ncbi.nlm.nih.gov/pubmed/24108091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2705
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