The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation

Activation by the Y-encoded testis determining factor SRY and maintenance of expression of the Sox9 gene encoding the central transcription factor of Sertoli cell differentiation are key events in the mammalian sexual differentiation program. In the mouse XY gonad, SOX9 upregulates Fgf9, which initi...

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Autori principali: Moniot, Brigitte, Declosmenil, Faustine, Barrionuevo, Francisco, Scherer, Gerd, Aritake, Kosuke, Malki, Safia, Marzi, Laetitia, Cohen-Solal, Anne, Georg, Ina, Klattig, Jürgen, Englert, Christoph, Kim, Yuna, Capel, Blanche, Eguchi, Naomi, Urade, Yoshihiro, Boizet-Bonhoure, Brigitte, Poulat, Francis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press for The Company of Biologists Limited 2009
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075598/
https://ncbi.nlm.nih.gov/pubmed/19429785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.032631
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