Embryonic MGE Precursor Cells Grafted into Adult Rat Striatum Integrate and Ameliorate Motor Symptoms in 6-OHDA-Lesioned Rats

We investigated a strategy to ameliorate the motor symptoms of rats that received 6-hydroxydopamine (6-OHDA) lesions, a rodent model of Parkinson’s disease, through transplantation of embryonic medial ganglionic eminence (MGE) cells into the striatum. During brain development, embryonic MGE cells mi...

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Detalhes bibliográficos
Main Authors: Martínez-Cerdeño, Verónica, Noctor, Stephen C., Espinosa, Ana, Ariza, Jeanelle, Parker, Philip, Orasji, Samantha, Daadi, Marcel M., Bankiewicz, Krystof, Alvarez-Buylla, Arturo, Kriegstein, Arnold R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075336/
https://ncbi.nlm.nih.gov/pubmed/20207227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.01.004
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