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Compounds used to produce cloned animals are genotoxic and mutagenic in mammalian assays in vitro and in vivo

The compounds 6-dimethylaminopurine and cycloheximide promote the successful production of cloned mammals and have been used in the development of embryos produced by somatic cell nuclear transfer. This study investigated the effects of 6-dimethylaminopurine and cycloheximide in vitro, using the thi...

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Bibliografische gegevens
Hoofdauteurs: Oliveira, R.J., Mantovani, M.S., da Silva, A.F., Pesarini, J.R., Mauro, M.O., Ribeiro, L.R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Associação Brasileira de Divulgação Científica 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075292/
https://ncbi.nlm.nih.gov/pubmed/24714812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20143301
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