Serotonergic Neurotoxic Thioether Metabolites of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”): Synthesis, Isolation and Characterization of Diastereoisomers

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a synthetic recreational drug of abuse that produces long-term toxicity associated with the degeneration of serotonergic nerve terminals. In various animal models direct administration of MDMA into the brain fails to reproduce the serotonergic neu...

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Autores principales: Pizarro, Nieves, de la Torre, Rafael, Joglar, Jesús, Okumura, Noriko, Perfetti, Ximena, Lau, Serrine S., Monks, Terrence J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075178/
https://ncbi.nlm.nih.gov/pubmed/19548351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx8002017
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