Convergence of IPMK and LKB1-AMPK Signaling Pathways on Metformin Action

Metformin is a biguanide drug that is widely prescribed for type 2 diabetes. Metformin suppresses hepatic gluconeogenesis and increases fatty acid oxidation. Although studies have suggested that metformin acts, at least in part, via activation of the liver kinase B1 (LKB1)/AMP-activated protein kina...

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Autori principali: Bang, Sookhee, Chen, Yong, Ahima, Rexford S., Kim, Sangwon F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075158/
https://ncbi.nlm.nih.gov/pubmed/24877601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1134
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