The BCL2 major breakpoint region is a sequence- and cell-cycle-specific binding site of the Ku antigen.
The majority of translocations involving BCL2 are very narrowly targeted to three breakpoint clusters evenly spaced over a 100-bp region of the gene's terminal exon. We have recently shown that the immediate upstream boundary of this major breakpoint region (mbr) is a specific recognition site for s...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10137 |
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