The specificity of the secondary DNA binding site of RecA protein defines its role in DNA strand exchange.

The RecA protein-single-stranded DNA (ssDNA) filament can bind a second DNA molecule. Binding of ssDNA to this secondary site shows specificity, in that polypyrimidinic DNA binds to the RecA protein-ssDNA filament with higher affinity than polypurinic sequences. The affinity of ssDNA, which is ident...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Mazin, A V, Kowalczykowski, S C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38213/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10673
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