Atg6/UVRAG/Vps34-Containing Lipid Kinase Complex Is Required for Receptor Downregulation through Endolysosomal Degradation and Epithelial Polarity during Drosophila Wing Development

Atg6 (Beclin 1 in mammals) is a core component of the Vps34 PI3K (III) complex, which promotes multiple vesicle trafficking pathways. Atg6 and Vps34 form two distinct PI3K (III) complexes in yeast and mammalian cells, either with Atg14 or with UVRAG. The functions of these two complexes are not enti...

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Main Authors: Lőrincz, Péter, Lakatos, Zsolt, Maruzs, Tamás, Szatmári, Zsuzsanna, Kis, Viktor, Sass, Miklós
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074780/
https://ncbi.nlm.nih.gov/pubmed/25006588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/851349
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