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Facile Access to Cyclooctanoid Ring Systems via Microwave-Assisted Tandem 6-exo dig Cyclization-Rearrangement Sequence

Appropriately substituted 5-alkyn-1-ol systems bearing a nitrile moiety at the triple bond serve as versatile precursors to a variety of cyclooctenone derivatives via a “one-pot” base-catalyzed oxyanionic 6-exo dig cyclization/Claisen rearrangement sequence under microwave irradiation. It was found...

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Detalhes bibliográficos
Main Authors: Feldman, Aaron W., Ovaska, Sami I., Ovaska, Timo V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074778/
https://ncbi.nlm.nih.gov/pubmed/24994941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.02.089
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