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Early VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activity

Although several potential mechanosensors/mechanotransducers have been proposed, the precise mechanisms by which ECs sense and respond to mechanical forces and translate them into biochemical signals remains unclear. Here, we report that two major ligand-dependent tyrosine autophosphorylation sites...

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Detalhes bibliográficos
Main Authors: dela Paz, Nathaniel G., Melchior, Benoît, Frangos, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074593/
https://ncbi.nlm.nih.gov/pubmed/23583373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.03.134
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