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FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1

The nematode worm Caenorhabditis elegans has been used to identify hundreds of genes that influence longevity and thereby demonstrate the strong influence of genetics on lifespan determination. In order to simplify lifespan studies in worms, many researchers have employed 5-fluoro-2′-deoxyuridine (F...

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Bibliographic Details
Main Authors: Van Raamsdonk, Jeremy Michael, Hekimi, Siegfried
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074524/
https://ncbi.nlm.nih.gov/pubmed/21893079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.08.006
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