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FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1

The nematode worm Caenorhabditis elegans has been used to identify hundreds of genes that influence longevity and thereby demonstrate the strong influence of genetics on lifespan determination. In order to simplify lifespan studies in worms, many researchers have employed 5-fluoro-2′-deoxyuridine (F...

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Autors principals: Van Raamsdonk, Jeremy Michael, Hekimi, Siegfried
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074524/
https://ncbi.nlm.nih.gov/pubmed/21893079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.08.006
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