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FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1

The nematode worm Caenorhabditis elegans has been used to identify hundreds of genes that influence longevity and thereby demonstrate the strong influence of genetics on lifespan determination. In order to simplify lifespan studies in worms, many researchers have employed 5-fluoro-2′-deoxyuridine (F...

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Detalhes bibliográficos
Main Authors: Van Raamsdonk, Jeremy Michael, Hekimi, Siegfried
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074524/
https://ncbi.nlm.nih.gov/pubmed/21893079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.08.006
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