Hypoxia induces downregulation of soluble guanylyl cyclase β(1) by miR-34c-5p

Soluble guanylyl cyclase (sGC) is the principal receptor for nitric oxide (NO) and crucial for the control of various physiological functions. The β(1) subunit of sGC is obligatory for the biological stability and activity of the sGC heterodimer. MicroRNAs (miRNAs) are important regulators of gene e...

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Bibliografiske detaljer
Main Authors: Xu, Xiaojian, Wang, Shumin, Liu, Juan, Dou, Dou, Liu, Limei, Chen, Zhengju, Ye, Liping, Liu, Huixia, He, Qiong, Raj, J. Usha, Gao, Yuansheng
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074291/
https://ncbi.nlm.nih.gov/pubmed/23038777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.113381
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