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Hypoxia induces downregulation of soluble guanylyl cyclase β(1) by miR-34c-5p

Soluble guanylyl cyclase (sGC) is the principal receptor for nitric oxide (NO) and crucial for the control of various physiological functions. The β(1) subunit of sGC is obligatory for the biological stability and activity of the sGC heterodimer. MicroRNAs (miRNAs) are important regulators of gene e...

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Detalhes bibliográficos
Main Authors: Xu, Xiaojian, Wang, Shumin, Liu, Juan, Dou, Dou, Liu, Limei, Chen, Zhengju, Ye, Liping, Liu, Huixia, He, Qiong, Raj, J. Usha, Gao, Yuansheng
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074291/
https://ncbi.nlm.nih.gov/pubmed/23038777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.113381
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