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Alu and LINE-1 Hypomethylation Is Associated with HER2 Enriched Subtype of Breast Cancer

The changes in DNA methylation status in cancer cells are characterized by hypermethylation of promoter CpG islands and diffuse genomic hypomethylation. Alu and long interspersed nucleotide element-1 (LINE-1) are non-coding genomic repetitive sequences and methylation of these elements can be used a...

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Detalhes bibliográficos
Main Authors: Park, So Yeon, Seo, An Na, Jung, Hae Yoen, Gwak, Jae Moon, Jung, Namhee, Cho, Nam-Yun, Kang, Gyeong Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074093/
https://ncbi.nlm.nih.gov/pubmed/24971511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100429
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