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GELSOLIN EXPRESSION INCREASES β(1)-INTEGRIN AFFINITY AND L1210 CELL ADHESION

Integrins are functionally regulated by “inside-out” signaling, in that stimulus-induced signaling pathways act on the intracellular integrin tail to regulate the activity of the receptor on the outside. Both a change in conformation (affinity) and clustering (avidity/valency) of the receptors occur...

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Detalhes bibliográficos
Main Authors: LANGEREIS, JEROEN D., KOENDERMAN, LEO, HUTTENLOCHER, ANNA, ULFMAN, LAURIEN H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074084/
https://ncbi.nlm.nih.gov/pubmed/23595955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21112
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