Epimorphin Alters the Inhibitory Effects of SOX9 on Mmp13 in Activated Hepatic Stellate Cells

BACKGROUND AND AIMS: Liver fibrosis is a major cause of morbidity and mortality. It is characterised by excessive extracellular matrix (ECM) deposition from activated hepatic stellate cells (HSCs). Although potentially reversible, treatment remains limited. Understanding how ECM influences the patho...

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Detalhes bibliográficos
Main Authors: Pritchett, James, Athwal, Varinder S., Harvey, Emma, Martin, Katherine, Llewellyn, Jessica, Ireland, Philip, Nicolaides, Alexander, Humphries, Martin J., Bobola, Nicoletta, Hanley, Neil A., Piper Hanley, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074045/
https://ncbi.nlm.nih.gov/pubmed/24971829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100091
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