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The GH/IGF-1 axis in ageing and longevity
Secretion of growth hormone (GH), and consequently that of insulin-like growth factor 1 (IGF-1), declines over time until only low levels can be detected in individuals aged ≥60 years. This phenomenon, which is known as the ‘somatopause’, has led to recombinant human GH being widely promoted and abu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074016/ https://ncbi.nlm.nih.gov/pubmed/23591370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2013.67 |
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