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The GH/IGF-1 axis in ageing and longevity

Secretion of growth hormone (GH), and consequently that of insulin-like growth factor 1 (IGF-1), declines over time until only low levels can be detected in individuals aged ≥60 years. This phenomenon, which is known as the ‘somatopause’, has led to recombinant human GH being widely promoted and abu...

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Detalles Bibliográficos
Main Authors: Junnila, Riia K., List, Edward O., Berryman, Darlene E., Murrey, John W., Kopchick, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074016/
https://ncbi.nlm.nih.gov/pubmed/23591370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2013.67
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