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Acetaldehyde disrupts tight junctions in Caco-2 cell monolayers by a protein phosphatase 2A-dependent mechanism

Acetaldehyde is accumulated at high concentrations in the colonic lumen following ethanol administration. Previous studies demonstrated that acetaldehyde disrupts intestinal epithelial tight junctions and increases paracellular permeability. In the present study, we investigated the role of PP2A in...

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Detaylı Bibliyografya
Asıl Yazarlar: Dunagan, Mitzi, Chaudhry, Kamaljit, Samak, Geetha, Rao, R. K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073985/
https://ncbi.nlm.nih.gov/pubmed/23064762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00526.2011
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