Independent Lineages of Highly Sulfadoxine-Resistant Plasmodium falciparum Haplotypes, Eastern Africa

Sulfadoxine-resistant Plasmodium falciparum undermines malaria prevention with sulfadoxine/pyrimethamine. Parasites with a highly resistant mutant dihydropteroate synthase (dhps) haplotype have recently emerged in eastern Africa; they negated preventive benefits of sulfadoxine/pyrimethamine, and mig...

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Hlavní autoři: Taylor, Steve M., Antonia, Alejandro L., Harrington, Whitney E., Goheen, Morgan M., Mwapasa, Victor, Chaluluka, Ebbie, Fried, Michal, Kabyemela, Edward, Madanitsa, Mwayi, Khairallah, Carole, Kalilani-Phiri, Linda, Tshefu, Antoinette K., Rogerson, Stephen J., ter Kuile, Feiko O., Duffy, Patrick E., Meshnick, Steven R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Centers for Disease Control and Prevention 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073871/
https://ncbi.nlm.nih.gov/pubmed/24960247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2007.131720
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