Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer

Trp63, founding member of the Trp53 family, contributes to epithelial differentiation and is expressed in breast neoplasia. Trp63 features two distinct promoters yielding specific mRNAs encoding two major TRP63 isoforms, a transactivating transcription factor and a dominant negative isoform. Specifi...

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Bibliografiske detaljer
Main Authors: Assefnia, Shahin, Kang, Keunsoo, Groeneveld, Svenja, Yamaji, Daisuke, Dabydeen, Sarah, Alamri, Ahmad, Liu, Xuefeng, Hennighausen, Lothar, Furth, Priscilla A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073690/
https://ncbi.nlm.nih.gov/pubmed/24692510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0032
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