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Immunologic Human Renal Allograft Injury Associates with an Altered IL-10/TNF-α Expression Ratio in Regulatory B Cells

Human B cells with immunoregulatory properties in vitro (Bregs) have been defined by the expression of IL-10 and are enriched in various B-cell subsets. However, proinflammatory cytokine expression in B-cell subsets is largely unexplored. We examined the cytokine profiles of human PBMCs and found th...

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Detalhes bibliográficos
Main Authors: Cherukuri, Aravind, Rothstein, David M., Clark, Brendan, Carter, Clive R., Davison, Adam, Hernandez-Fuentes, Maria, Hewitt, Eric, Salama, Alan D., Baker, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073434/
https://ncbi.nlm.nih.gov/pubmed/24610932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080837
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