Role of Podocyte B7-1 in Diabetic Nephropathy

Podocyte injury and resulting albuminuria are hallmarks of diabetic nephropathy, but targeted therapies to halt or prevent these complications are currently not available. Here, we show that the immune-related molecule B7-1/CD80 is a critical mediator of podocyte injury in type 2 diabetic nephropath...

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Detalhes bibliográficos
Main Authors: Fiorina, Paolo, Vergani, Andrea, Bassi, Roberto, Niewczas, Monika A., Altintas, Mehmet M., Pezzolesi, Marcus G., D’Addio, Francesca, Chin, Melissa, Tezza, Sara, Ben Nasr, Moufida, Mattinzoli, Deborah, Ikehata, Masami, Corradi, Domenico, Schumacher, Valerie, Buvall, Lisa, Yu, Chih-Chuan, Chang, Jer-Ming, La Rosa, Stefano, Finzi, Giovanna, Solini, Anna, Vincenti, Flavio, Rastaldi, Maria Pia, Reiser, Jochen, Krolewski, Andrzej S., Mundel, Peter H., Sayegh, Mohamed H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073425/
https://ncbi.nlm.nih.gov/pubmed/24676639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013050518
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