Severe Renal Mass Reduction Impairs Recovery and Promotes Fibrosis after AKI

Preexisting CKD may affect the severity of and/or recovery from AKI. We assessed the impact of prior graded normotensive renal mass reduction on ischemia-reperfusion–induced AKI. Rats underwent 40 minutes of ischemia 2 weeks after right uninephrectomy and surgical excision of both poles of the left...

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Bibliografische gegevens
Hoofdauteurs: Polichnowski, Aaron J., Lan, Rongpei, Geng, Hui, Griffin, Karen A., Venkatachalam, Manjeri A., Bidani, Anil K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2014
Onderwerpen:
Basic Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073422/
https://ncbi.nlm.nih.gov/pubmed/24511135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013040359
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