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Premalignant PTEN-deficient thymocytes activate microRNAs miR-146a and miR-146b as a cellular defense against malignant transformation

Cancer develops by a multistep process during which cells acquire characteristics that allow them to evade apoptosis and proliferate unchecked. Sequential acquisition of genetic alterations drives this process but also causes cellular stress, frequently prompting cells to enter a premalignant period...

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Bibliografski detalji
Glavni autori: Burger, Megan L., Xue, Ling, Sun, Yuefang, Kang, Chulho, Winoto, Astar
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073325/
https://ncbi.nlm.nih.gov/pubmed/24735967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-539411
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