Vaccine for Cocaine Dependence: A Randomized Double-Blind Placebo-Controlled Efficacy Trial

AIMS: We evaluated the immunogenicity, efficacy, and safety of succinylnorcocaine conjugated to cholera toxin B protein as a vaccine for cocaine dependence. METHODS: This 6-site, 24 week Phase III randomized double-blind placebo-controlled trial assessed efficacy during weeks 8 to 16. We measured ur...

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Главные авторы: Kosten, Thomas R., Domingo, Coreen B., Shorter, Daryl, Orson, Frank, Green, Charles, Somoza, Eugene, Sekerka, Rachelle, Levin, Frances R., Mariani, John J., Stitzer, Maxine, Tompkins, D. Andrew, Rotrosen, John, Thakkar, Vatsal, Smoak, Benjamin, Kampman, Kyle
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073297/
https://ncbi.nlm.nih.gov/pubmed/24793366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2014.04.003
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