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Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer

The mechanisms through which cancer cells lock in altered transcriptional programs in support of metastasis remain largely unknown. Through integrative analysis of clinical breast cancer gene expression datasets, cell line models of breast cancer progression, and mutation data from cancer genome res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vanharanta, Sakari, Marney, Christina B, Shu, Weiping, Valiente, Manuel, Zou, Yilong, Mele, Aldo, Darnell, Robert B, Massagué, Joan
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073284/
https://ncbi.nlm.nih.gov/pubmed/24898756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02734
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