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Ataxia telangiectasia derived iPS cells show preserved x-ray sensitivity and decreased chromosomal instability
Ataxia telangiectasia is a neurodegenerative inherited disease with chromosomal instability and hypersensitivity to ionizing radiation. iPS cells lacking ATM (AT-iPS cells) exhibited hypersensitivity to X-ray irradiation, one of the characteristics of the disease. While parental ataxia telangiectasi...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4073166/ https://ncbi.nlm.nih.gov/pubmed/24970375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05421 |
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