Mechanisms and consequences of hepatic regulation of mTORC1 by metformin

Gelijkaardige items

• Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex
  door: Howell, Jessica J., et al.
  Gepubliceerd in: (2017)
• mTORC1 stimulates nucleotide synthesis through both transcriptional and post-translational mechanisms
  door: Ben-Sahra, Issam, et al.
  Gepubliceerd in: (2014)
• Oncogenic signaling upstream of mTORC1 drives lipogenesis and proliferation through SREBP
  door: Ricoult, Stéphane, et al.
  Gepubliceerd in: (2014)
• Pathological Consequences of Hepatic mTORC1 Dysregulation
  door: Cho, Chun-Seok, et al.
  Gepubliceerd in: (2020)
• The multifaceted role of mTORC1 in the control of lipid metabolism
  door: Ricoult, Stéphane J H, et al.
  Gepubliceerd in: (2013)