Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation

BACKGROUND: Tumour-derived extracellular vesicles (EVs) play a role in tumour progression; however, the spectrum of molecular mechanisms regulating EV secretion and cargo selection remain to be fully elucidated. We have reported that cavin-1 expression in prostate cancer PC3 cells reduced the abunda...

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Autori principali: Inder, Kerry L., Ruelcke, Jayde E., Petelin, Lara, Moon, Hyeongsun, Choi, Eunju, Rae, James, Blumenthal, Antje, Hutmacher, Dietmar, Saunders, Nicholas A., Stow, Jennifer L., Parton, Robert G., Hill, Michelle M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Co-Action Publishing 2014
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072912/
https://ncbi.nlm.nih.gov/pubmed/25018864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v3.23784
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