Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1

Polymerase I and transcript release factor (PTRF, also known as Cavin-1) is an essential component in the biogenesis and function of caveolae. Here, we show that PTRF expression is increased in senescent human fibroblasts. Importantly, overexpression of PTRF induced features characteristic of cellul...

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Autori principali: Bai, Lin, Deng, Xiaoli, Li, Juanjuan, Wang, Miao, Li, Qian, An, Wei, A, Deli, Cong, Yu-Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193497/
https://ncbi.nlm.nih.gov/pubmed/21445100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.56
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