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Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1
Polymerase I and transcript release factor (PTRF, also known as Cavin-1) is an essential component in the biogenesis and function of caveolae. Here, we show that PTRF expression is increased in senescent human fibroblasts. Importantly, overexpression of PTRF induced features characteristic of cellul...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193497/ https://ncbi.nlm.nih.gov/pubmed/21445100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.56 |
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