Discovery of a Novel Compound with Anti-Venezuelan Equine Encephalitis Virus Activity That Targets the Nonstructural Protein 2

Alphaviruses present serious health threats as emerging and re-emerging viruses. Venezuelan equine encephalitis virus (VEEV), a New World alphavirus, can cause encephalitis in humans and horses, but there are no therapeutics for treatment. To date, compounds reported as anti-VEEV or anti-alphavirus...

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Main Authors: Chung, Dong-Hoon, Jonsson, Colleen B., Tower, Nichole A., Chu, Yong-Kyu, Sahin, Ergin, Golden, Jennifer E., Noah, James W., Schroeder, Chad E., Sotsky, Julie B., Sosa, Melinda I., Cramer, Daniel E., McKellip, Sara N., Rasmussen, Lynn, White, E. Lucile, Schmaljohn, Connie S., Julander, Justin G., Smith, Jeffrey M., Filone, Claire Marie, Connor, John H., Sakurai, Yasuteru, Davey, Robert A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072787/
https://ncbi.nlm.nih.gov/pubmed/24967809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004213
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