Discovery of a Novel Compound with Anti-Venezuelan Equine Encephalitis Virus Activity That Targets the Nonstructural Protein 2

Alphaviruses present serious health threats as emerging and re-emerging viruses. Venezuelan equine encephalitis virus (VEEV), a New World alphavirus, can cause encephalitis in humans and horses, but there are no therapeutics for treatment. To date, compounds reported as anti-VEEV or anti-alphavirus...

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Hlavní autoři: Chung, Dong-Hoon, Jonsson, Colleen B., Tower, Nichole A., Chu, Yong-Kyu, Sahin, Ergin, Golden, Jennifer E., Noah, James W., Schroeder, Chad E., Sotsky, Julie B., Sosa, Melinda I., Cramer, Daniel E., McKellip, Sara N., Rasmussen, Lynn, White, E. Lucile, Schmaljohn, Connie S., Julander, Justin G., Smith, Jeffrey M., Filone, Claire Marie, Connor, John H., Sakurai, Yasuteru, Davey, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072787/
https://ncbi.nlm.nih.gov/pubmed/24967809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004213
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